Tip on Making it Easier to Medicate your Cat
For cats on a routine medication, the best time to "treat" your cat is just before feeding time. Most cats will learn that there is a reward after the "pill" and deal with pill time much better than any other time of day.
For cats on twice daily mediations, consider offering a canned "treat time" twice daily just before pill time.
For more tips on medicating your cat, read Flavored Medications for Cats.